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Revista Cubana de Pediatría

versão On-line ISSN 1561-3119

Resumo

ROIG ALVAREZ, Tania et al. Congenital cytomegalovirus infection in very low birth weight neonates. Rev Cubana Pediatr [online]. 2024, vol.96  Epub 13-Mar-2024. ISSN 1561-3119.

Introduction:

Congenital cytomegalovirus infection in neonates weighing less than 1500 grams can be a cause of morbidity, mortality, and disability.

Objective:

To describe the behavior of congenital cytomegalovirus infection in a neonatal service.

Methods:

A descriptive and cross-sectional study was conducted with 61 neonates. Cytomegalovirus was detected in the first week of life in serum and urine, by polymerase chain reaction, to determine congenital infection. Perinatal variables were evaluated in all neonates, as well as clinical elements and results of complementary examinations in infected infants.

Results:

The incidence of congenital infection was 10% (6/61). 5% of the studies were positive (6/122). No urine samples were positive (0/61) and the virus genome was detected in 10% of serum samples (6/61). An association was found between nutritional assessment at birth and cytomegalovirus infection (p < 0.05). A total of 83% of infected neonates had some clinical sign, with respiratory distress syndrome being the most common (67%). In all neonates with congenital infection, brain ultrasound was normal, and retinopathy of prematurity was detected in 33% of patients with fundus retinopathy.

Conclusions:

The incidence of congenital cytomegalovirus infection is high in this risk group. The clinical signs found and the results of the fundus in neonates with congenital infection were related to prematurity and the nutritional assessment of hypotrophic was associated with this infection.

Palavras-chave : congenital cytomegalovirus; cytomegalovirus; very low birth weight neonate..

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