Revista Cubana de Obstetricia y Ginecología
versión On-line ISSN 1561-3062
SARDUY NAPOLES, Miguel. Cytohistological correlation in cervical intraepithelial neoplasias and in detection of HPV in these types of lesions. Rev Cubana Obstet Ginecol [online]. 2009, vol.35, n.1, pp. 0-0. ISSN 1561-3062.
Organ cytology of cervix and the histological study of dysplasias or of lesions caused by the human papillomavirus (HPV) together with colposcopy are the basis supporting the diagnosis of cervical intraepithelial neoplasia and their correlation offers a good diagnostic indicator for HPV. OBJECTIVES: to set the diagnostic correlation between cytology and histology in cervical intraepithelial neoplasias (CIN) diagnosis and to detect the presence of human papilloma virus through cytology and histology in patients with dysplastic lesions in the uterine neck. METHODS: a prospective open research study was performed on a group of 205 females with cytological diagnosis of cervical intraepithelial neoplasia. Of this amount, 150 were diagnosed as CIN II and CIN III whereas 55 were classified as CIN I at the Gynecology Service of the Medical and Surgical Research Center (CIMEQ) from 1994 to 2005. RESULTS: cytological diagnosis agreed with the biopsy results in 97,3% of high degree lesions and in 90,9% of low degree lesions. Human papilloma virus was present in eight out of 10 women with low degree lesions (CIN I) and in seven out of 10 women with high degree lesions (CIN II and III). CONCLUSIONS: when there are high degree cervical intraepithelial lesions, the cytological and histological correlation is more accurate. Histology is more effective in diagnosing human papilloma virus infection than cytology.
Palabras llave : Organ cytology; cervix biopsy; HPV; CIN.