Resumen

FRONTELA NODA, Maydelín; RODRIGUEZ MARIN, Yoima; RIOS HERNANDEZ, María de los Ángeles  y  HERNANDEZ MENENDEZ, Maite. Chlamydia trachomatis. Rev Cubana Obstet Ginecol [online]. 2014, vol.40, n.1, pp. 68-78. ISSN 0138-600X.

It has been shown that human papillomavirus presence is a necessary condition for the development of cervical cancer. However, it is not sufficient and only a small number of exposed women will progress to cervical neoplasia. Proposed cofactors include other sexually transmitted infections, smoking habit, hormones, nutritional deficiencies, obesity and host genetic/immunologic responses. Chlamydia trachomatis is the most common bacterial sexually transmitted infection and it has been associated with the development of cervical cancer in many case-controlled and population based studies. However, it is still necessary to elucidate some aspects of cause/effect relationship between Chlamydia trachomatis infection, human papillomavirus persistence and progression to cervical cancer. This article aims to review the current scientific literature upon the role of Chlamydia trachomatis as a cofactor in the development of invasive cervical cancer and HPV establishment. Prophylaxis against Chlamydia trachomatis could be important in reducing the incidence of cervical cancer, mainly in young women.

Palabras clave : Chlamydia trachomatis; cervical cancer; human papillomavirus (HPV).

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