Resumen

INFANTE VELAZQUEZ, Mirtha et al. Caracterización clínica de un brote de hepatitis aguda por virus A en una institución cerrada. Rev Cub Med Mil [online]. 2002, vol.31, n.4. ISSN 0138-6557.

Acute viral hepatitis is an important cause of morbidity among the personnel working or staying in closed facilities. In order to identify the clinical serological behavior of pro-hepatitis A virus during an epidemic outbreak, it was conducted a descriptive study including the longitudinal follow-up of 123 patients with icterus and elevation of transaminases as diagnosed criteria of the affection. Those cases with subclinical or unapparent disease (non-icteric) were not taken into consideration. Each patient underwent a monthly determination of aminotranferases and bilirubin until its normalization and a survey including demographic variables and clinical symptoms and signs was done. 97.5 % of the cases were males with an average age of 19.8 years old (DE = 2.35 years old). The prevailing symptoms were asthenia (95.9 %) in the prodromic period and icterus (100 %) in the icteric phase. 89.4 % developed a classical acute icteric hepatitis, 8.9 % the relapsing or diphase and 1.6 % the cholestatic form. In the latter, the bilirubin figures were higher (p = 0.0028). The cholestatic variant extended to 31.4 weeks and the diphasic (p = 0.001) to 29.96 weeks. It was concluded that the disease has a benign evolution that may be easily managed by the basic assistance and that there are clinical forms prolonguing the time of affectation of the physical capacities of the patient.

Palabras clave : HEPATITIS VIRAL; HUMAN; DISEASE OUTBREAKS; MORBIDITY; MEN; EPIDEMIOLOGY DESCRIPTIVE; LONGITUDINAL STUDIES.