Abstract

RAMOS CONTRERAS, Juan Yerandy; BRIZUELA QUINTANILLA, Raúl; WINOGRAD LAY, Rebeca  and  ANGULO PEREZ, Omar. Gastric acidity, Helicobacter pylori and giardiasis in patients with ulcerous syndrome. Preliminary report. Rev Cub Med Mil [online]. 2008, vol.37, n.4. ISSN 0138-6557.

OBJECTIVE: To assess the role of gastric acidity, the Helicobacter pylori infection, and giardiasis in the diseases manifested as an ulcerous syndrome. METHODS: A cross-sectional, analytical and prospective study was conducted. An upper endoscopy with sample-taking was performed to study the gastric mucosa status, as well as urease test, duodenal smear, and gastrochemogram in 54 patients with clinical manifestations of ulcerous syndrome. RESULTS: Gastritis was the most frequent endoscopic diagnosis (29/54; 50.8 %). We found patterns of hypo- and hyperacidity without significant differences (p = 0.817. The presence of Helicobacter pylori was very high (p = 0.001) without differences in the cases of ulcer (p = 0.804) or gastritis (p = 0.743). A relation between H. pylori infection and the presence of changes in the secretory pattern of acid (p = 0,001) was proved. No positive relation was observed between the H.pylori joint infection and Giardia lamblia (p = 0.176). CONCLUSIONS: There is a high association between H.pylori infection, endoscopic, histological and secretory lesion in patients with a clinic of ulcerous syndrome.

Keywords : Ulcerous syndrome; peptic ulcer; gastritis, and Helicobacter pylori.

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