Abstract

MULET PEREZ, Agustín et al. Clinical, humoral, laparoscopic and hystic hepatic alterations in blood donors showing positive hepatitis virus C antibody test results . Rev Cub Med Mil [online]. 2009, vol.38, n.1. ISSN 0138-6557.

An observational and descriptive study was made on 69 blood donors, who had positive C virus antibodies detected by the provincial blood bank and had been referred to "Vladimir Ilich Lenin" provincial university hospital from January 2000 to December 2006. They were performed translaparoscopic hepatic biopsy. For the purpose of estimating clinical, humoral, laparoscopic and histopathological hepatic disorders, the biopsy request forms were checked. Chronic hepatitis predominated, with minimal activity (12; 33.335) and slight activity (13; 36.1 %). Most of patients were asymptomatic (62; 89.9 %) and their transaminase values were normal (47; 68.1 %). Laparoscopy was a very specific test showing 84.4 % specificity, with a high value (75 %) in a positive test for chronic hepatitis diagnosis. However, low figures of sensitivity (41 %) and of the predictive value in a negative test (57.1 %) for chronic hepatitis diagnosis reaffirmed that hepatic biopsy continues to be the golden test for the diagnosis of this disease.

Keywords : HCV antibody; chronic hepatitis C; diagnosis; blood donors..

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )