Resumo

MONTERO GONZALEZ, Teresita et al. Non-alcoholic hepatic steatosis prevalence in necropsies and related metabolic morphologic alterations. Rev Cub Med Mil [online]. 2011, vol.40, n.1, pp.32-39. ISSN 0138-6557.

INTRODUCTION: the liver disease due to non-alcoholic fat depot corresponds to hepatic morphologic alterations excluding the alcohol consumption. OBJECTIVE: to identify the hepatic steatosis prevalence in the autopsies study. METHODS: the medical records from adult deceased from 1991 to 2009 in the "Dr. Luis Díaz Soto" Central Military Hospital were reviewed. The alcoholics and the carriers of viral liver diseases (acute and chronic) were excluded. Cases were grouped according to following variables: age groups, related metabolic diseases and the major cause of death. A total of 669 medical records were reviewed to assess the body mass index to relate it to results. RESULTS: all age groups showed affections due to steatosis more frequent between 55 and 84 years. In the 3 317 deceased with non-alcoholic fat-depot liver disease, it was noted the presence of simple liver steatosis, steatohepatitis in 1 468 cases and hepatic steatosis with fibrosis or cirrhosis in 88 cases. In almost the 50 % of cases the steatosis was moderate intensity. The 34.3 % showed pancreas/myocardium stromal fat infiltration. Only the 7.5 % of study cases had not a atherosclerotic lesion. The 59.2 % of cases presenting with simple steatosis showed a body mass index over 30. The major basic cause of death was the coronary atherosclerosis (24.5 %). CONCLUSIONS: the diseases related to metabolic syndrome show their morphologic alterations with a high frequency. The hepatic steatosis, particularly the liver disease due to non-alcoholic fat depot, is a disorder with a high prevalence among the alterations found in study autopsies.

Palavras-chave : Non-alcoholic fat liver; autopsy; atherosclerosis.

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