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Revista Cubana de Medicina Militar

versión On-line ISSN 1561-3046


MARTINEZ MARTIN, Sara María et al. In vivo healing activity of the charred powder of Punica granatum Linn and Eichhornia crassipes. Rev Cub Med Mil [online]. 2019, vol.48, n.2  Epub 01-Jun-2019. ISSN 1561-3046.


Plant species are the first remedy to the people's health problems. The pomegranate is rich in ascorbic acid, improves the epidermal barrier and reduces the contraction of wounds. The water hyacinth has antibacterial activity.


To evaluate the healing effect of the charred powder of Punica granatum Linn (pomegranate) and Eichhornia crassipes (water hyacinth), in an experimental model in rats.


Experimental analytical study with 30 male rats distributed in 3 groups (n = 10). Group I and II; treated with the charred powder of the pomegranate and water hyacinth respectively. Group III: treated with 0.9 % sodium chloride. An incision wound model was made on the back. The evolution of healing was followed by the speed of contraction of the wound in millimeters. Histology was performed on biopsies of scar tissue. For the statistical analysis, the nonparametric Mann-Whitney test was used. The level of significance was set at p < 0.05.


The healing effect of the charred powders of the pomegranate and water hyacinth was verified; decreased the wound area significantly compared to the control group. The histological study showed mature grade III dermis in groups I and II.


The topical application of the charred powder of pomegranate and water hyacinth influenced the closure of the wounds and the maturation of the dermis, which favored healing.

Palabras clave : wounds; cicatrizing activity; Punica granatum Linn; Eichhornia crassipes.

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