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Revista Cubana de Medicina Militar

versión impresa ISSN 0138-6557versión On-line ISSN 1561-3046

Resumen

NUNEZ GARLOBO, Daniel Lázaro et al. Mean platelet volume and possible prognostic value in patients with acute myocardial infarction. Rev Cub Med Mil [online]. 2019, vol.48, n.4, e421.  Epub 01-Dic-2019. ISSN 0138-6557.

Introduction:

Numerous factors are related to in-hospital complications in patients with acute myocardial infarction, the usefulness of the mean platelet volume as a prognostic factor is currently controversial.

Objective:

To describe the association between mean platelet volume in patients with acute myocardial infarction, with cardiovascular risk factors and clinical evolution.

Method:

Observational study in 188 patients with acute myocardial infarction, who were admitted to the Cardiology Department of the Central Military Hospital "Dr. Carlos J. Finlay ". The following complications were monitored: cardiac death, heart failure, post-infarction angina, reinfarction and all combined. Platelet volume was determined by automated blood count at admission and <9 fL and ≥ 9 fL were used as cut-off values.

Results:

The male sex (69.7%) and over 50 years (91.5%) predominated. Hypertensive, diabetic and smoking patients presented higher platelet volume (82.9%, p = 0.00; 90.4%, p = 0.03; 89.1%, p = 0.00 respectively). 22.3% presented combined complications; Heart failure (45.2%) and post-infarction angina (3.3%) were the most frequent. Heart failure was the complication associated with high platelet volume (p = 0.027). Platelet volume ≥ 9 fL was an independent predictor of adverse events (p = 0.00; 95% CI: 3.89-112.908).

Conclusions:

The high mean platelet volume was associated with worse intrahospital clinical evolution and heart failure the most prevalent complication. It was also associated with high blood pressure, smoking and diabetes mellitus.

Palabras clave : mean platelets volume; ST elevation; acute myocardial infarction, complications.

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