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Características clínicas y epidemiológicas de pacientes con la COVID-19 y trastornos quimiosensoriales


 
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Revista Cubana de Medicina Militar

 ISSN 1561-3046

LORENZO GONZALEZ, Sergio César et al. Clinical and epidemiological characteristics of COVID-19 patients with chemosensory disorders. []. , 50, 4   01--2021. ISSN 1561-3046.

Introduction:

Chemosensory disorders have been identified as typical symptoms of COVID-19.

Objective:

To characterize patients with COVID-19 and referred chemosensory disorders.

Methods:

One hundred and fifty-two hospitalized patients, positive for COVID-19, with referred chemosensory disorders were included. Clinical and epidemiological variables, inflammation markers, chest X-ray and treatment used were studied.

Results:

The average age was 40.2 years, the female sex 59.2%. The antecedent of confirmed case contact (62.5 %), anosmia (95.7 %), ageusia (93.3 %), and the absence of comorbidities (53.3 %) and accompanying symptoms (36.8 %), prevailed. In patients with an indeterminate source of infection, confirmation was late (3.89 days); there were no significant differences between those who presented one or both disorders (p = 0.053), nor between those who did or did not present associated symptoms (p = 0.14). In 2 % the neutrophil index was greater than 4; 3.3 % had an absolute lymphocyte count lower than 1500x106/L and 68.4 % did not show radiological alteration. Antimicrobials were required in 5.9 % and immunomodulators in 5.3 %; 1.3 % were admitted to intensive care. Most (95.4 %) were discharged from the clinic and 1.3 % died.

Conclusions:

The female sex predominates, with ageusia or anosmia; those who do not have an epidemiological background are diagnosed with delay. There are no differences in seeking care, for one or both disorders, or for accompanying symptoms. Chemosensory disorders are more referred in the absence of complications and severe disease. Those who refer them spontaneously are generally healthy and oligosymptomatic people.

: COVID-19; SARS-CoV-2; smell disorders; taste disorders; anosmia; ageusia.

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