SciELO - Scientific Electronic Library Online

 
vol.38 issue1An enzyme-linked immunosorbent assay (ELISA) for serological detection of antibodies against Borrelia in calves in BrazilToxicosis in goat by Mulato grass (Brachiaria ruziziensis- Brachiaria brizantha) in Artemisa province author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista de Salud Animal

Print version ISSN 0253-570XOn-line version ISSN 2224-4700

Abstract

CORONA GONZALEZ, Belkis et al. Analysis of major surface protein 1a sequence in Cuban isolates of Anaplasma marginale. Rev Salud Anim. [online]. 2016, vol.38, n.1, pp.14-18. ISSN 0253-570X.

The bovine anaplasmosis is a disease of cattle caused by the rickettsia Anaplasma marginale. The major surface proteins encoded by genes with conserved sequences are potential candidates for vaccines. Among these proteins, MSP1a is expressed by a single copy gene (msp1a). The molecular weight of MSP1a varies among A. marginale isolates from different geographical regions due to the presence, in a variable number, of a sequence of 28-29 amino acids in tandem repeats. In the present study, the sequences of the repeats and of the microsatellite of the protein MSPla of two isolates of A. marginale from bovines in a farm of the Cuban western region were examined. Both isolates belongs to the genotype G, and the isolate 21G presented the repeats T-B-B-C and the 25G of the types T-C. The analysis of these repeated sequences are very important because they include markers for transmissibility by ticks and are of great value for the future development of a vaccine candidate against this hemoparasite.

Keywords : bovine anaplasmosis; msp1a; MSP1a; major surface proteins.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License