Revista Cubana de Medicina Tropical
versión On-line ISSN 1561-3054
GONZALEZ, TANIA et al. Evolución de la resistencia en una cepa de Culex quinquefasciatus a partir de la selección con el insecticida piretroide lambdacialotrina. Rev Cubana Med Trop [online]. 1996, vol.48, n.3, pp. 218-223. ISSN 1561-3054.
The resistance change to different insecticides in Culex quinquesfasciatus strain select at the laboratory with doses of pyrethroid lambda-cyhalothrin that would cause a larva mortality of 90 % were studied. It was attained an increase of the resistance to this insecticide of 144.5 times compared with the original level, and it was obtained a resistant strain (287x). There was an increase of the levels of resistance to methyl-pyrimifos (2.4 times), propoxur (6 times), DDT (5,2 times), clorpirifos (22 time), cypermethrin (67.5 times), and deltamethrin (20.2 times). The frecuencies of the genes that codify for the elevated esterases enzymes and for the modified acetylcholinesterase reached their maximum value. Significant changes were observed in the phenotypes for esterases in the electrophoresis in polyacralamide gels. It was detected synergism of DEF and PB with lambda-cyhalothrin. Therefore, the elevated esterases and the esterases of multiple function may contribute to resistance.
Palabras llave : INSECTICIDE RESISTANCE; CULEX [enzymology].