Abstract

MAS LAGO, Pedro; AVALOS REDON, Ivonne; BELLO CORREDOR, Marité  and  PALOMERA PUENTES, Rosa. Características antigénicas de los virus aislados del líquido cefalorraquídeo de pacientes con neuropatía epidémica. Rev Cubana Med Trop [online]. 1998, vol.50, suppl.1, pp.231-234. ISSN 0375-0760.

During the epidemic of neuropathy occurred in Cuba from 1992 to 1994 viral agents antigenically related to the Coxsackie viruses were isolated from the cerebrospinal fluid of patients. To establish a function of these viruses in the etiopathogeny of the disease, strains 47/93 IPK identified as Coxsackie A9 and the strain 44/93 of light cytopathic effect were selected to conduct a study of their antigenic characteristics by Western Blot. It was proved that there is an antigenic relationship between both strains and it was also demonstrated the absence of structural proteins in their native form among the agents of light cytopathic effect. According to these results, it is stated the possibility that persistance may be a mechanism through which these viruses take part in the etiopathogeny of epidemic neuropathy in Cuba.

Keywords : NEURITIS [cerebrospinal fluid]; NEURITIS [etiology]; COXSACKIE VIRUSES [isolation & purification]; CUBA.

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