Revista Cubana de Medicina Tropical
On-line version ISSN 1561-3054
GARCIA, Humberto; SANCHEZ, Javier and ORTEGA, Liz. Diagnóstico topográfico de lesiones del sistema nervioso simpático en la neuropatía epidémica cubana. Valor de la respuesta simpática cutánea. Rev Cubana Med Trop [online]. 1998, vol.50, suppl.4, pp. 245-248. ISSN 1561-3054.
The purpose of this study is to demonstrate from the electrophysiological point of view the existance of disorders of the autonomic nervous system (ANS) and to deepen in the probable topography of the lesions. The sympathetic skin response (SSR) was studied in 37 patients with Cuban epidemic neuropathy (CEN) and in 29 sound individuals. The response to electrical stimulation with simultaneous registry in the 4 limbs was assessed. The latencies and amplitudes of the SSR registered in the lower limbs of patients were significantly different from those of the controls (p < 0.05). This difference between both groups was not observed in the upper limbs. These results are an objective and reproducible evidence of the injury of the ANS in the Cuban epidemic neuropathy. The highest intensity of affectation of the amplitudes of the SSR of lower limbs, with relative indemnity of those of the upper limbs, suggests a predominance of the axonal injury of the peripheral efferent branch towards the lower limbs that is congruent with the greatest affectation of the peripheral nerves in this localization.
Keywords : SYMPATHETIC NERVOUS, AUTONOMIC [injuries]; SYMPATHETIC NERVOUS, AUTONOMIC [physiology]; ELECTRIC STIMULATION; CUBA.