Abstract

GARCIA, Gissel et al. Detección de respuesta linfoproliferativa en monos inoculados con virus dengue 4. Rev Cubana Med Trop [online]. 2003, vol.55, n.1, pp.27-29. ISSN 0375-0760.

A group of 6 Cynomolgus monkeys was immunized with dengue 4 virus (H247 standard strain). 60 days after innoculation the cellular proliferation against the same serotype as well as against hetereologous serotypes 1 and 2 was measured. A proliferative response predominantly of the specific serotype and some cross reactivity were detected. These results showed a behavior of primates similar in some extent to that of human beings and mice regarding the specific serotype and cross serotype response to dengue virus.

Keywords : DENGUE VIRUS [immunology]; DENGUE [immunology]; MACACA FASCICULARIS; DISEASE MODELS; ANIMAL: T-LYMPHOCYTES [immunology].

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