Abstract

MENDOZA, Daimary et al. Utilidad de 2 métodos coproparasitológicos y su empleo en un ensayo terapéutico antigiardiásico. Rev Cubana Med Trop [online]. 2003, vol.55, n.3, pp.174-178. ISSN 0375-0760.

A study of 456 children aged 1-5 from 4 day care centers of San Miguel del Padrón municipality was conducted in November, 1998, to evaluate the diagnosis of Giardia lamblia and other intestinal protozoa by using comparatively the coproparasitological diagnostic methods of direct examination and Ritchie's concentration technique or formol-ether. Besides, a therapeutical trial was developed with tinidazole and albendazole for treating the infection caused by G. lamblia. Ritchie's concentration technique was more effective than the microscopic direct examination for diagnosing Giardia lamblia, Entamoeba histolytical/Entamoeba dispar and Cyclospora cayetanensis. It was demonstratyed that the serial examination was more sensitive than the analysis of just one sample (p< 0.01). On the other hand, tinidazole proved to be more efficient than albendazole to treat the infection produced by G. lamblia, with a greater cure percentage (72 % vs. 334.6 %), (p < 0.01).

Keywords : GIARDIA LAMBLIA [drug effects]; GIARDIA LAMBLIA [parasitology]; GIARDIASIS [diagnosis]; GIARDIASIS [parasitology]; GIARDIASIS [drug therapy]; TINIDAZOLE [therapeutic use]; ALBENDAZOLE [therapeutic use]; FECES [parasitology]; CHILD, PRESCHOOL; SCHOOLS, NURSERY; CLINICAL TRIALS.

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