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Revista Cubana de Medicina Tropical

Print version ISSN 0375-0760On-line version ISSN 1561-3054

Abstract

NUNEZ, . Juan Francisco et al. Evaluation of two different potency tests for leptospirosis vaccine vax-SPIRAL®. Rev Cubana Med Trop [online]. 2005, vol.57, n.1, pp.67-68. ISSN 0375-0760.

Two different potency tests were evaluated, consisting in one-dilution used to determine 50 % lethal dose (LD50) and four-dilution used to calculate 50 % effective dose (ED50), respectively. Our experience has led to propose the four-dilution test for routine lot releasing.

Keywords : Vax-SPIRAL; leptospirosis; potency test.

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