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Revista Cubana de Medicina Tropical
versión impresa ISSN 0375-0760versión On-line ISSN 1561-3054
Resumen
FERNANDEZ ENRIQUE, Kenia et al. Use of diafiltration in the lavage of cultures of Leptospira interrogans canicola canicola for the production of vaccine vax-SPIRAL. Rev Cubana Med Trop [online]. 2005, vol.57, n.1, pp.69-70. ISSN 0375-0760.
It was proposed to substitute the present technology of the lavage operation for a tangential microfiltration system at the lavage stages of the culture of Leptospira interrogans canicola canicola. It was proved that this system may be applied, since no cellular affectation was observed and high pollutant elimination levels were obtained.
Palabras clave : Vax-SPIRAL; leptospirosis; diafiltration.