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Revista Cubana de Medicina Tropical

versión impresa ISSN 0375-0760versión On-line ISSN 1561-3054


OTERO GONZALEZ, Anselmo J.. The antibodies and their role as analytic tools in immunoenzymatic assays. Rev Cubana Med Trop [online]. 2010, vol.62, n.2, pp.85-92. ISSN 0375-0760.

This paper presented the history and evolution of the antibodies since their discovery. It also elucidated their complex structure and function that have served at a given time as methodological basis for creating unimaginable paradigms such as fine recognition specificity, and also for destroying other apparently immutable ones as invariability and universality of the cellular genome. A review was made of the evolution of antigen-antibody reaction-based analytical systems up to the present, the situation of infectious diseases and the determining role that detection and monitoring of infectious agents play in their control. The extraordinary capability of antibodies to discriminate antigenically similar structures allows them to be fundamental tools in immunoassays and also in a well-established discipline at present, that is, immunotechnology.

Palabras clave : antibodies; specificity; immunoassays; infectious agents; immunodetection.

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