SciELO - Scientific Electronic Library Online

 
vol.66 issue3Aeromycology and human healthInsecticidal resistance profiles of an Aedes aegypti (Linnaeus) strain from the Caribbean Region of Costa Rica author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Revista Cubana de Medicina Tropical

On-line version ISSN 0375-0760

Abstract

DADE, Martín Miguel; DANIELE, Martín Rafael; PIA SILVESTRINI, María  and  MESTORINO, Nora. In vitro efficacy of three endectocides against Triatoma infestans. Rev Cubana Med Trop [online]. 2014, vol.66, n.3, pp.338-350. ISSN 0375-0760.

Introduction: various studies have demonstrated the role that areas around the houses play in domiciliary re-infestation by Triatomainfestans (kissing bugs). With the aim of removing residual foci of T. infestans that inhabit in neighboring areas of houses, different strategies have been developed. The administration of different anti-T. infestans compounds to animals living in areas around the houses might be a good way to reduce the risk of domiciliary re-infestation. Objective: to evaluate the in vitro efficacy of three antiparasitic agents, doramectin (DRM), ivermectin (IVM) and eprinomectin (EPR) against fifth instar nymphs of Triatomainfestans. Methods: artificial feeders were designed , which contained heparinized and fortified blood with various concentrations of the three endectocides (100-0.4 ng/mL). We used 600 fifth instar nymphs of T. infestans during the experiment. A group of insects were fed with untreated blood (control). After feeding they were under observation to check their condition every 24 hours for a week. Results: the three molecules showed activity against T. infestans. In comparing the activity of the three molecules, DRM exhibited greater potency against insects, it even kept its activity against T. infestans at 0.4 ng/mL (lowest concentration tested). In the case of EPR and IVM, their efficacy began to lower at concentrations below 6.25 and 3.15 ng/mL respectively, being totally inactive at 0.4 ng/mL concentration. Conclusions: Based on these results, we can assert that under our experimental conditions, IVM, EPR and DRM show in vitro high efficacy against T. infestans, being the latter more effective than the other two molecules.

Keywords : Chagas disease; Triatomainfestans; mortality; endectocides.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License