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Revista Cubana de Hematología, Inmunología y Hemoterapia
versión impresa ISSN 0864-0289versión On-line ISSN 1561-2996
Resumen
CABRERA ROJAS, Humberto et al. Pulmonary alveolar proteinosis in hematologic patients: Report of 2 cases. Rev Cubana Hematol Inmunol Hemoter [online]. 1999, vol.15, n.3, pp.221-226. ISSN 0864-0289.
Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by the accumulation of protein in the pulmonary alveoli of the affected individuals. In patients with hematologic diseases it has been reported an incidence of PAP of 5.3 %, of which 10 % corresponds to disorders in the granulopoietic lines. This entity has also been observed in the course of chronic myeloid leukemia (CML). In this paper 2 cases of hematologic patients are presented. The first was a 54-year-old woman with CML who died due to respiratory failure. The second was a 49-year-old female carrier of medullary aplasia after a treatment with chloramphenicol that presented symptoms of respiratory infections repeatedly until her final admission and death. Both patients were diagnosed on necropsy. A review of the literature was made
Palabras clave : PROTEINOSIS ALVEOLAR PULMONAR [sangre]; MEDULA OSEA [anomalía]; LEUCEMIA MIELOIDE CRONICA; PULMONARY ALVEOLAR PROTEINOSIS [blood]; BONE MARROW [abnormalities]; LEUKEMIA, MYELOID, CHRONIC.