Resumen

MESA CUERVO, José René et al. Respiratory functional changes in patients with sickle cell anemia and history of acute chest synd. Rev Cubana Hematol Inmunol Hemoter [online]. 2002, vol.18, n.2. ISSN 0864-0289.

A prospective descriptive study was made to evaluate the respiratory function in patients with sickle cell anemia and history of acute chest syndrome seen at the outpatient service of the Institute of Hematology and Immunology from September 1999 to September 2000. The universe of study was divided into 2 groups: the first was made up of 36 patients diagnosed with sickle cell anemia and history of acute thoracic syndrome; and the second included 17 patients with sickle cell anemia, distributed by age and sex in a similar way as in the first one, but without history of acute chest syndrome. All the selected patients were applied the respiratory function tests according to the international criteria. Restrictive respiratory dysfunction was observed in all patients with sickle cell anemia regardless of their history of acute chest syndrome; however, the history of two or more syndromes showed the highest percentages. Age and sex did not influence the results

Palabras clave : ANEMIA, HEMOLYTIC, CONGENITAL [complications]; ANEMIA SICKLE CELL [complications]; RESPIRATORY FUNCTION TESTS [methods]; PULMONARY EMBOLISM; LUNG DISEASES, SPIROMETRY.