SciELO - Scientific Electronic Library Online

 
vol.23 número1Efecto in vitro del Ateromixol sobre los linfocitos y neutrófilos humanosPurificación de la proteína banda 3 de eritrocitos humanos (AE 1) índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO

Compartir


Revista Cubana de Hematología, Inmunología y Hemoterapia

versión impresa ISSN 0864-0289versión On-line ISSN 1561-2996

Resumen

VILLAESCUSA BLANCO, Rinaldo et al. Natural anti-band 3 antibodies: Do they take part in the phenomenon of vasoocclusion drepanocytosis. Rev Cubana Hematol Inmunol Hemoter [online]. 2007, vol.23, n.1. ISSN 0864-0289.

The presence of natural anti-band 3 antibodies was determined by an immunoenzymatic assay in microplaques coupled with band 3 protein in 14 patients with drepanocytosis, 4 with painful vasoocclusive crisis and 10 in the basal state. It was proved a significant reduction (p = 0,000005) of the levels of natural anti-band 3 antibodies in all the patients on comparing them with the normal controls, which may be related to an elevated consumption of these in the clearance process of oxidized or senescent erythrocytes with hemoglobin SS. There was no statistical difference between the group of patients in the basal state and those with painful vasoocclusive crisis, which suggests that the natural anti-band 3 antibodies do not take part in the modulation of the occlusive phenomenon that is produced in this disease. The longitudinal study of a greater number of patients that allows to go deep into this apect is recommended

Palabras clave : natural anti-band 3 antibodies; painful vasoocclusive crisis; drepanocytosis; band 3 protein.

        · resumen en Español     · texto en Español

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons