Revista Cubana de Hematología, Inmunología y Hemoterapia
versión On-line ISSN 1561-2996
MARSAN SUAREZ, Vianed et al. Oral leukoplasia in a pediatric patient with primary deficiency of T lymphocytes. Rev Cubana Hematol Inmunol Hemoter [online]. 2010, vol.26, n.1, pp. 62-69. ISSN 1561-2996.
Presence off recurrent infections caused by uncommon germs related to appearance of frequent complications and associated with allergic and autoimmune and/or tumor manifestations, are characteristic of primary immunodeficiencies. Authors present the case of a white male child aged 12, with backgrounds of viral, bacterial and parasitic, recurrent and severe infections, from the first months of life, with a diagnosis of non-homogenous oral leukoplasia of tongue, supported by histopathology. Viral study showed the presence of antibodies specific to viral capsid and of nuclear antigen of Epstein-Barr virus. Immunologic studies showed the presence of a primary immunodeficiency of T lymphocytes. There were not alterations in serum concentrations of immunoglobulins, the complement and the phagocytic function. Surgical removal of lesion and the use of immunomodulation contributed to a favorable course of patient.
Palabras llave : T lymphocytes primary deficiency; oral leukoplasia; Epstein-Barr virus.