Abstract

CASTILLO-GONZALEZ, Dunia de la C.; LAMBERT-GARCIA, Miriam; ALMAGRO-VAZQUEZ, Delfina  and  SALINAS-GONZALEZ, Jorge L.. Association of immunologic thrombocytopenia and the Guillain-Barré syndrome. Rev Cubana Hematol Inmunol Hemoter [online]. 2010, vol.26, n.4, pp.345-351. ISSN 0864-0289.

The immunologic thrombocytopenic purpura is an autoimmune, benign, of frequent appearance disease characterized by the presence of antibodies directed to glycoproteins of platelet membrane producing a decrease of platelet count and cutaneous-mucosal hemorrhagic manifestations. The Guillain-Barré syndrome is also a disease autoimmune by origin where the loss of immunological tolerance causes the appearance of antibodies directed to gangliosides of peripheral nerves. This is the case of female patient aged 40 diagnosed with a chronic immunologic thrombocytopenic purpura beginning with an ascendant motor paralysis, without respiratory compromise, facial paralysis and intense pain in dorsal and lumbar regions and also a diagnosis of Guillain-Barré syndrome with immediate treatment based on vitamin-therapy and high dose of steroids. After some months of follow-up and rehabilitation there was a satisfactory evolution with remission of all neurological symptoms.

Keywords : Autoimmune thrombocytopenia purpura; Guillain-Barré syndrome; ascendant motor paralysis.

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