Resumen

DORTICOS-BALEA, Elvira et al. Updating in transplant of hematopoietic progenitor cells in pediatric patients during the past 15 years. Rev Cubana Hematol Inmunol Hemoter [online]. 2011, vol.27, n.1. ISSN 0864-0289.

In the past year 2010, it was commemorate the 25 Anniversary of introduction in Cuba of the bone marrow transplantation and its development has followed the sequence of the universal history of the hematopoietic transplantation. In present paper authors made reference to more important achievements over the past 15 years including the introduction of the transplantation with mobilized cell to peripheral blood. Partial results of a comparative study of 2 groups of pediatric patients are showed; one received hematopoietic progenitor cells obtained from the bone marrow and other with cells mobilized to the peripheral blood by means of hematopoietic growth factors. Other advances include: the introduction of non-myeloablation transplantation in 2002, the application of recombinant factors produced in Cuba in the management of transplanted patients and the introduction of chimerism. Different features related to histocompatibility are analyzed as well as the requirements to improve the transplantation results. It is indicated the contribution of the experience obtained with this procedure for the development of the regenerative medicine.

Palabras clave : Transplantation; allogenic; autologous; bone marrow; peripheral blood.

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