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Revista Cubana de Hematología, Inmunología y Hemoterapia

versión impresa ISSN 0864-0289

Resumen

CRUZ-CAMEJO, Yaniurka et al. Cutaneous Rosai-Dorfman disease: a propos of a case. Rev Cubana Hematol Inmunol Hemoter [online]. 2013, vol.29, n.1, pp.90-98. ISSN 0864-0289.

A 50 year-old patient with a painless round tumoral lesion on inguinal region with progressive growth and formation of an eritematous plaque with areas of pigmentation, infiltration of deep tissues and apparition of other lesions with tumoral aspect is described. The anatomopathological study showed a hystiocitic infiltrate with linfohystiofagocitosis phenomenon (Emperipolesis) and the immunohystochemical made evident positive for Vimentine, S-100, CD68 and Lisozime. The available scientific evidence of the international literature was reviewed to determine the most frequent clinical manifestations of this disease, as well as most updated means of diagnosis employed and the treatment of this disease. It is important to consider the cutaneous Rosai-Dorfman disease as one of the possible diagnosis so a profound study of the biopsy is essential, as well as the immunohystochemical studies due to the mildness and good prognosis of this disease.

Palabras clave : cutaneous Rosai-Dorfman disease; rare diseases; emperipolesis.

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