Resumen

SAAVEDRA HERNANDEZ, Danay. CD28 and its role in T cell activation. Rev Cubana Hematol Inmunol Hemoter [online]. 2013, vol.29, n.4, pp.359-367. ISSN 0864-0289.

CD28 is a very important correceptor among T cells and provide positive signals that promote and sustain T-cell responses. In the last few years, CD 28 has become an interesting target in grafts and autoimmune diseases. This review will focus on the mechanisms whereby CD28 allowing a complete T cell activation.

Palabras clave : costimulation; CD28; T cell signaling.

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