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Revista Cubana de Hematología, Inmunología y Hemoterapia

Print version ISSN 0864-0289On-line version ISSN 1561-2996

Abstract

LA ROSA HERNANDEZ, Deyanira; SANCHEZ CASTANEDA, Niurka; VILLA JIMENEZ, Oscar  and  GOMEZ CABEZAS, Enrique J. Common variable immunodeficiency and selective IgA deficiency in celiac disease patients. Rev Cubana Hematol Inmunol Hemoter [online]. 2016, vol.32, n.3, pp.394-402. ISSN 0864-0289.

Celiac disease (CD) is an autoimmune gastrointestinal disease very often associated with Primary Immunodeficiencies (PID) as selective IgA deficiency and variable immunodeficiency common. About the link between celiac disease IDP, two female patients diagnosed as celiac patients with different forms of presentation and varying commitment immunonutritional presented. Low levels of immunoglobulin G (IgG) and absence of immunoglobulin A (IgA) were the main humoral findings recorded, no commitment of B and T cells, according to the quantification of lymphoid subpopulations by flow cytometry. Nutritional and immunological intervention allowed remission of clinical manifestations and satisfactory outcome in both cases.

Keywords : celiac disease; selective IgA deficiency; common variable immunodeficiency.

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