Abstract

HERNANDEZ REYES, Laser H; FUNDORA SARRAFF, Teresa A; JANERO VALDES, Alexis  and  HERNANDEZ RAMIREZ, Porfirio. Radioisotopic image: an efficient tool in regenerative therapy. Rev Cubana Hematol Inmunol Hemoter [online]. 2017, vol.33, n.2, pp.1-9. ISSN 0864-0289.

Regenerative therapy is nowadays a promising alternative treatment for many diseases. The utility of radioisotope image technologies in assessing of the efficiency and security of stem cell therapies is described. We present some of the facts that led to development of the nuclear medicine image technology, as well as the general characteristics of single photon emission computed tomography and positron emission tomography. It was also included application of radioisotope images in the evaluation of biodistribution changes, flow and perfusion in anatomical affected zones by different diseases, in the fields of angiology, orthopedia and cardiology, as a result of the regenerative and proliferative effects induced by stem cells transplant. We mention the radiopharmaceuticals and labelled molecules used in the evaluation of angiogenesis and lymph angiogenesis resulting of cellular therapy and the radioisotopes markers that allow tracking of transplanted stem cells.

Keywords : regenerative medicine; stem cells; nuclear medicine; single photon emission computed tomography; positron emission tomography.

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