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Revista Cubana de Hematología, Inmunología y Hemoterapia
versión impresa ISSN 0864-0289versión On-line ISSN 1561-2996
Resumen
MARTINEZ SANCHEZ, Lina Maria et al. Residual minimal disease: breaking the paradigm of complete remission. Rev Cubana Hematol Inmunol Hemoter [online]. 2018, vol.34, n.1, pp.21-32. ISSN 0864-0289.
Hematological malignancies constitute a heterogeneous group of conditions. Residual minimal disease (RMS) refers to the presence of haematological malignancy in patients who are in remission if conventional pathological analyzes are used. RMS has been shown to have prognostic significance in conditions such as: acute myeloid leukemia, chronic myeloid leukemia, multiple myeloma, and acute and chronic lymphoblastic leukemia. Ultrasensitive detection of this condition could allow a better risk stratification and open opportunities for early therapeutic interventions. In the following article there will be a brief review about the prognostic importance of RMS in different hematologic malignancies.
Palabras clave : neoplasm residual; flow cytometry; prognosis.