Introduction:

Irregular antibodies correspond to those other than natural anti-A or anti-B antibodies, which may appear in response to exposure to a foreign erythrocyte antigen (transfusion or transplantation) or due to maternal-fetal incompatibility.

Objective:

To characterize the donors with positive irregular antibody screening of a blood bank in Monteria, Colombia during the period 2012-2015.

Methods:

Cross-sectional and retrospective study, with secondary information source, based on the results of the antibody screening in donors of a blood bank in Monteria, Colombia from 2012 to 2015. The population consisted of all voluntary donors registered in the study time (35 248 donors), who were screened for antibodies. As a sample, all cases that had positive results (71 donors) were selected. The data was organized in tables and analyzed in the software SPSS 21.0, Microsoft Excel and in Epidat version 3.1.

Results:

0.2% of the population presented a positive antibody screen with a confidence interval between 0.15 and 0.25%. Irregular antibodies were more frequent in men and in O Rh positive donors. Thirteen types of irregular antibodies were found, with predominance of anti-M, anti-Lea, anti-D and anti-E and respective percentages of 27.78%, 20.83%, 9.72% and 8.33%. 50% of the donors were 30.5 years old or less, 49.3% had previously donated and 9.9% received at least one transfusion at some point in their lives.

Conclusion:

The frequency of donors with irregular positive antibody screening was low, the male sex had a higher percentage, it was detected mainly in blood group O and within the irregular antibodies, anti-M showed a higher frequency.

        · resumen en Español     · texto en Español     · Español ( pdf )