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Revista Cubana de Hematología, Inmunología y Hemoterapia

versión On-line ISSN 1561-2996

Resumen

SANCHEZ ACOSTA*, Zuzet; FIGUEROA SAEZ, Juan Antonio; GAMEZ PEREZ, Anadely  y  FORRELLAT BARRIOS, Mariela. Organ failures and early death in critically ill patients with non-promyelocytic acute myeloid leukemia. Rev Cubana Hematol Inmunol Hemoter [online]. 2025, vol.41  Epub 05-Sep-2025. ISSN 1561-2996.

Introduction:

Predicting survival through the identification of prognostic risk factors in intensive care units is an essential tool in the care of critically ill patients with non-promyelocytic acute myeloid leukemia.

Objective:

To analyze organ failure and early death in critically ill patients with non-promyelocytic acute myeloid leukemia.

Methods:

An observational, longitudinal, ambispective, and analytical clinical study was conducted, including 19 critically ill patients diagnosed with non-promyelocytic acute myeloid leukemia who were admitted to intensive care. Qualitative and quantitative analyses of the study variables were performed.

Results:

Female patients younger than 50 years of age were most associated with early death. The Organ Failure Scale score was higher in deceased patients, and mortality progressively increased in patients with higher scores.

Conclusions:

Predictive factors associated with early death in patients with non-promyelocytic AML in the induction phase of treatment do not differ from those found in the general population during critical illness, so offering support in the ICU to patients with this disease gives them a chance of survival.

Palabras clave : non-promyelocytic acute myeloid leukemia, prognostic factors; organ failures.

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