Resumen

ZUMAETA VILLENA, Eduardo; GONZALEZ GRIEGO, Antonio; RAMIREZ ALBAJES, Victoria  y  FIGUEROA BARRIOS, Rolando. Inmunogenicidad de la vacuna recombinante cubana contra la hepatitis B en trabajadores de la salud peruanos. Rev Cubana Invest Bioméd [online]. 2000, vol.19, n.1, pp.45-50. ISSN 0864-0300.

We researched into the immunogenicity (seroconversion, hyperesponse and geometric mean) caused by the Cuban recombinant anti-B viral hepatitis in Cuba in a national concurrent multicenter study. The 0, 1 and 2 month immunization schedule was used in 211 sensitive health workers who worked for the Peruvian Institute of Social Security. The immunoenzymatic method called Organon Teknika. 97% seroprotection was reached just in 75 days after the vaccination schedule started; higher immunogenicity was observed in under 40 years-old women. We recommended the implementation of this schedule as part of the control program of B hepatitis because of its simetry, short latency and level of protection

Palabras clave : VACCINES,SYNTHETIC [immunology]; VACCINES SYNTHETIC [administration and dosage]; HEPATITIS B VACCINES [administration and dosage]; HEALTH PERSONNEL; PERU.

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