SciELO - Scientific Electronic Library Online

 
vol.19 número1Evaluación y control de un brote epidémico de hepatitis viral en escolares guineanos: Eficacia de heberbiovac HBRespuesta pos-vacunal y persistencia de anticuerpos contra el virus de la hepatitis B en niños asmáticos y no asmáticos vacunados con eberbiovac-HB índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO

Compartilhar


Revista Cubana de Investigaciones Biomédicas

versão impressa ISSN 0864-0300versão On-line ISSN 1561-3011

Resumo

ALMEIDA, Ricardo; GONZALEZ RAMIREZ, Gisela; GONZALEZ GRIEGO, Antonio  e  RAMIREZ ALBAJES, Victoria. Durabilidad de la respuesta inmune contra el vhb en niños de un círculo infantil en Cuba. Rev Cubana Invest Bioméd [online]. 2000, vol.19, n.1, pp.76-90. ISSN 0864-0300.

The Ministry of Public Health of Cuba sets out to wipe out viral hepatitis B for the year 2000. To attain this goal, it implemented a National Program which started in 1991 with the immunization of children from Hepatitis B carrier mothers and was extended to all neonates from 1992 on. One of the parameters to evaluate immunogenicity of a vaccine is durability of post-vaccine response that permits to prove whether a reinforcement dose is needed or not. Taking the importance of this type of study into account, the levels of antibodies to HBV (anti-HbsAg) were quantified in the children of a day-care center who were vaccinated as part of the National Immunization Program. These children were distributed by years of life: First year(I), 19 children; second year (II) 10; third year (III) 31; fourth year (IV) 24; and firth year (V) 22, totalling 106 children. The serological samples were assessed by ELISA in the Department of Immunology of the "Victoria de Girón" Institute of Basic and Pre-clinical Sciences. In each studied group, the number of children with seroprotection (10 UI/L or higher) and hyperesponse (100 UI/L or higher) were determined. Additionally, the arithmetic mean was calculated. The levels of seroprotection and hyperesponse were over 93 and 76% respectively. The arithmetic mean was over 181 UI/L in all the studied groups

Palavras-chave : IMMUNIZATION; PROGRAMS; HEPATITIS B VACCINES [immunology]; VACCINES, SYNTHETIC HEPATITIS B SURFACE ANTIGENS [analysis]; MASS VACCINATION; CHILD DAY CARE CENTERS.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons