Resumo

CASTANO OSORIO, Jhon Carlos  e  SARRACENT PEREZ, Jorge. Inmunización intranasal de ratones con la proteína SAG2 de Toxoplasma gondii asociada con la toxina colérica. Rev Cubana Invest Bioméd [online]. 2002, vol.21, n.1, pp.35-45. ISSN 0864-0300.

The capacity of SAG2 native protein from the Toxoplasma gondii tachyzoite as an immunogen administered by intranasal route associated with cholera toxin in mice was studied. The group of animals immunized with SAG2 protein without adjuvant presented a smaller charge of cerebral cysts after the challenge by oral route with T. gondii 76K strain cysts. The presence of specific antibodies against this protein, both at the serological level (IgG) and in saliva (IgA), was proved in all the animals that received SAG2 in the immunisation scheme.

Palavras-chave : IMMUNOASSAY; ANTIBODIES, PROTOZOAN; ADMINISTRATION, INTRANASAL; MICE.

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