Revista Cubana de Investigaciones Biomédicas
On-line version ISSN 1561-3011
NASIFF-HADAD, Alfredo et al. Modificaciones de los lípidos y lipoproteínas del plasma en obesos dislipidémicos sometidos a reducción ponderal a corto plazo con la dieta Cambridge. Rev Cubana Invest Bioméd [online]. 2002, vol.21, n.4, pp. 221-227. ISSN 1561-3011.
64 patients of both sexes aged 22-65 and with a body mass index over 30 kg/m2 were studied aimed at determining the effect of Cambridges diet as a unique dietary support (411-548 kcal/d) during 8 weeks.on cholesterol, triglycerides, high density lipoproteins and low desity lipoproteins in a group of dyslipidemic obese patients (cholesterol 5.2 mmol/L), who were divided into 2 groups of 32 subjects each: 1. Dyslipidemic obeses that were not affected by hypertension or diabetes mellitus. 2. Non-dyslipidemic obese patients that had no hypertension or diabetes mellitus. The following variables were evaluated: weight (kg), hip circumference (cm), systolic and diastolic pressure, total cholesterol, triglycerides, HDLc aand LDLc. The percentages of variation of every analyzed variable were calculated at each stage of its determination in relation to the basal value and its statistical significance was obtained by the Students t test. A substantial reduction of body weight (approximately 10 kg), hip circumference, systolic and diastolic pressure, and of the serum levels of total cholesterol, triglycerides and LDLc, as well as an increase of HDLc were observed. These modifications were more significant during the first week of treatment than in any other. Cambridges diet is a dietary option to attain favorable changes of cholesterol, triglycerides, serum lipoproteins among obese patients undergoing a short-term weight reducing program.
Keywords : OBESITY [diet therapy]; OBESITY [metabolism]; HYPERLIPIDEMIA; LIPOPROTEINS; WEIGHT LOSS; DIET, REDUCING.