Resumo

CESPEDES, Ela M.  e  REYES, Alberto. Oxidative stress markers in aged rats. Rev Cubana Invest Bioméd [online]. 2007, vol.26, n.2. ISSN 0864-0300.

A study of oxidative damage and anti-oxidizing defense markers in organs from young, adult and aged rats was conducted. It was evident that lipid peroxidation in liver, heart, kidneys and pancreas increases with the time as well as anti-oxidizing enzyme catalase reduces its action in all the organs except for pancreas. Changes at the time of aging have been associated with an imbalance in oxidizing and anti-oxidizing mechanisms within the cells. The results showed a state of oxidative stress that favors the occurrence of aging-related diseases.

Palavras-chave : aging; lipid peroxidation; anti-oxidizing enzymes; oxidative stress.