Resumo

HERNANDEZ TRIANA, Manuel  e  RUIZ ALVAREZ, Vladimir. Obesity, a world epidemics: Genetic implications. Rev Cubana Invest Bioméd [online]. 2007, vol.26, n.3. ISSN 0864-0300.

The literature review on body overweight and obesity disclosed alarming figures worldwide. Figures provided by studies conducted in Cuba were similar and included adults as well as children. This tendency grows as diabetes and blood hypertension increase, both factors having a joint incidence on morbidity and mortality from chronic diseases. Prevention of body overweight and chronic diseases, an issue included in the World Health Organization strategies, has been consequently structured with a preventive approach throughout life. Changes in lifestyles comprising food and regular exercising have determining influence in the world tendencies for these diseases. Human genome has slightly varied in its evolution; however, trascendental changes have occured in the lifestyle of the last 2 to 3 generations leading to explosive behaviour of these problemas at the international level. The increased knowledge of gene-nutrient interaction is revolutionizing the management of huge epidemics that will appear in this century. Particular examples on genes linked to the metabolism of energy, fat acids, folic acid, appetite control, energy output, tolerance to glucose and fat depot in the human body. The preparation of intervention programs aimed at the control of these disease should take this diversity into account.

Palavras-chave : Obesity; genetics; nutrigenomic; nutrigenetics; prevalence; Cuba.

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