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Revista Cubana de Investigaciones Biomédicas

Print version ISSN 0864-0300

Abstract

FERNANDEZ ARGONES, Liamet et al. Modifications of posterior ocular anterior segment with peripheral laser iridotomy. Rev Cubana Invest Bioméd [online]. 2011, vol.30, n.3, pp.301-311. ISSN 0864-0300.

OBJECTIVE: To evaluate post-laser peripheral iridotomy variations of anterior ocular segment by anterior segment optical coherence tomography. METHOD: Prospective observational case series in 30 patients (46 eyes) diagnosed with primary angle- closure suspect. The tomography was obtained pre-operative and at seven days post-operative by SL-OCT Heidelberg Engineering. Quantitative variables related to anterior segment structures were analyzed before and after the laser peripheral iridotomy treatment. RESULTS: There were no pre-operative statistical differences between quadrants. In the pos-op period all variables showed significant differences particularly at inferior and nasal quadrant, except for iris-scleral spur distance (p=0.926) and angle opening distance at 750µm (p=0.069). Pos-laser changes were significant for variables related to the angle (p=0.000), anterior chamber volume (p=0.000), and anterior chamber depth (p=0.011). The average increase in post-laser anterior chamber angle was 8.7±5.9 degrees and it was correlated negatively to pre-operative iris-scleral spur distance (p=0.007), angle opening distance at 500µm (p=0.031), trabecular-iris space area at 500 µm (p=0.003), and 750µm (p= 0.026). Inter-eye differences were non significant for post-operative changes. CONCLUSION: Laser iridotomy is effective to increase the anterior chamber angle, and it is associated with the increase in anterior chamber volume and central depth in primary angle- closure suspect

Keywords : laser iridotomy; optical coherence tomography of anterior segment.

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