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Revista Cubana de Investigaciones Biomédicas

versión On-line ISSN 1561-3011


PATINO BELLO, Diana Paola et al. Use of biocides and bacterial response mechanisms. Rev Cubana Invest Bioméd [online]. 2018, vol.37, n.3, pp. 1-17. ISSN 1561-3011.

The constant appearance of microorganisms that increase their tolerance to substances used for their control such as biocides is generating attention in public health and should be studied, taking into account the various risks that can be faced mainly in patients with high susceptibility to infections associated with health care, given that these biocides are used on a daily basis, which has generated bacterial mechanisms such as the formation of biofilms and those that increase their tolerance, such as the generation of flow pumps. This bacterial response to the pressure of the biocides is enhanced by the appearance of microorganism's resistant to the antimicrobials used in the treatment and control of infections, which makes their control difficult. A literature review was made available in the databases Proquest, ovid, Science direct, PubMed, where a total of 103 articles were found and 73 were selected, according to the year of publication in the Spanish and English languages, which included Descriptive and review studies. The objective of this article is to carry out a review about the main action mechanisms of biocides and the tolerance response presented by microorganisms against them; which leads to reflection on the implications of the use of these substances on human health.

Palabras clave : biocides; bacteria; resistance; genes; flow pumps; mechanism of action.

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