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Revista Cubana de Investigaciones Biomédicas

versión On-line ISSN 1561-3011


RAMIREZ ESTEVA, Osmay Ediberto et al. Fluctuations of zinc homeostatics related to the human growth-development stages. Rev Cubana Invest Bioméd [online]. 2018, vol.37, n.3, pp. 1-16. ISSN 1561-3011.

It is known that the Factor of Insulin Dependent Growth I (IGF-I), it diminishes their expression in presence of plasmatic deficit of zinc. The objective of the present revision is to relate fluctuations of the homeostasis of the zinc with stages of the human growth-development. Of the discussion of it dates it presented one has that: the human growth-development is a process with incidences of the calcium and of the zinc, where the deficit of zinc is a factor of high risk for the premature birth of infants and of children with drop carves; enough evidences exist to infer a direct weak association between the gradual increment of the plasmatic levels of zinc and calcium with the increase of the age during the childhood and the adolescence and that the interaction of collaboration between the calcium and the zinc in the osteogenesis, suffers a differentiation of functions in the enchondral ossification , and it becomes a competition relationship in the formation of the dental enamel ; it is manifested as tendency an increment of the plasmatic zinc with the increase of the age, with due biases to the overweight and the obesity and to the woman's productive fertility. Then it can be considered finally that the homeostasis of the plasmatic zinc, stabilized in an interval of normal values for a given stadium, favorable the necessary and enough growth-development being the aging an involution moment in that tendency of increment of plasmatic values of zinc with the age.

Palabras clave : Stages of the growth-development; fluctuations in the homeostasis of the zinc.

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