SciELO - Scientific Electronic Library Online

 
 issue67Matching between prospective and reactive methods for risk analysis in ionizing radiation medicine author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Nucleus

Print version ISSN 0864-084XOn-line version ISSN 2075-5635

Abstract

AGUILERA CORRALES, Yuri; LLANES MONTESINO, Luis Enrique; DIAZ PAEZ, Ahmed  and  ESPINO LOPEZ, Raquel. Labeling of silica sand with 99mTc for obtaining a solid radiotracer. Nucleus [online]. 2020, n.67, pp.39-43.  Epub July 23, 2020. ISSN 0864-084X.

To obtain 99mTc solid radiotracers, new porous supports are currently needed. Previous studies carried out by other authors showed the possibility of 99mTc labeling of sediments from rivers with a high content of aluminosilicates. In the present work a methodology for labeling of silica sand with 99mTcO4- as a prospective solid radiotracer was developed. Labeling of the previously treated and untreated silica sand was carried out using variable concentrations of chloride and stannous fluoride as reducing agents and different labeling times. The influence of the pre-treatment stage of the sand on the obtained Tc retention yields was evaluated. The changes in the composition of the silica sand after its previous treatment could be verified from the Scanning Electron Microscopy (SEM-EDS). The results suggested the use of previously treated silica sand and stannous fluoride as a reducing agent, modifications were proposed to the initial methodology of previous treatment of the sand. It was possible to confirm from the SEM-EDS technique that the increase in the percentage of retention of Tc in the sand after its treatment is mainly due to the observed changes in its chemical composition and structure. It was possible to obtain a 99mTc solid radiotracer on support of silica sand with an estimated preparation time of 4 hours and a retention yield of 74%.

Keywords : silica; technetium 99; reducing agents; labelling; tracer techniques; labelled compounds.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )