Resumen

DYCE GORDON, Elisa; CHIKUY FERRA, Miriam; ORTIZ MAGARINO, Carlos  y  DYCE GORDON, Lilian. Registro y análisis de algunas variables epidemiológicas relacionadas con las malformaciones congénitas mayores. Rev Cubana Med Gen Integr [online]. 1999, vol.15, n.4, pp.430-435. ISSN 0864-2125.

A case-control study on some epidemiological variables connected with the 42 most clinically severe major congenital malformations reported in 2 health areas of Camagüey municipality from January, 1986,to December, 1994, was conducted. Data were obtained from the forms of the Provincial Registry of Congenital Malformations, death certificates, family medical histories of the family physicians offices, medical histories of genetic risk and pediatrics and from interviews to parents. The most frequent malformations were those of the cardiovacular system. Histories of miscarriage and threatened abortion were related to 9,52 and 21,6 % of the malformed, respectively. A possible causal association with alcohol ingestion, exposure to heat and flu was found. The relationship between the maternal ingestion of tranquilizers and analgesics and the presence of malformations was statistically significant. These environmental factors must be avoided during pregnancy and a close surveillance must be kept in the areas, which is possible through the registry of these defects.

Palabras clave : ABNORMALITIES; EPIDEMIOLOGY FACTORS; CASE-CONTROL STUDIES; RECORDS.

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