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Revista Cubana de Medicina General Integral
Print version ISSN 0864-2125On-line version ISSN 1561-3038
Abstract
LLAMOS PANEQUE, Aicha Julia et al. Analysis of the congenital malformations detected by the alpha-fetoprotein-genetic ultrasound program. Rev Cubana Med Gen Integr [online]. 2007, vol.23, n.1. ISSN 0864-2125.
The alpha-fetoprotein is a specific glycoprotein of the fetal plasma, whose determination in maternal serum is performed from the 15th to the 19th week of gestation. This research was conducted to know the behavior of the alpha-fetoprotein-genetic ultrasound program in “10 de Octubre” municipality. It was found that 108 pregnant women presented elevated alpha-fetoprotein in maternal serum during the analyzed period. The main causes depending on the mother were: error in the date of the last menstruation and threatened abortion. The most frequent congenital malformations were the defects of the neural tube closure, and the cardiovascular malformations.
Keywords : Alpha-fetoprotein; congenital malformations; genetic diseases..