Resumo

MENA CANTERO, Alvin  e  VALDES GONZALEZ, Griselda. Leptine:. Rev Cubana Med Gen Integr [online]. 2009, vol.25, n.3. ISSN 0864-2125.

INTRODUCTION: leptine has a significant role in obesity pathogeny, which informs to hypothalamus of the body fat content and regulates the food consumption; however, this hormone is a elementary mediator of some physiologic functions in our organism. METHODS: a bibliographic review was carried out including a total of 32 data from Endocrinology specialty, to describe the physiologic mechanism of Leptine, and its relation with diverse neuroendocrine disorders. RESULTS: concentrations of Leptine are lower in male sex a feature related to the testosterone increase exerting an inhibitory effect on its production. Among other physiologic effects is the regulation of puberty onset and it is involved in inflammatory response. CONCLUSIONS: nowadays, obesity treatment possibilities and other fertility disorders related to use of Leptine are open.

Palavras-chave : Leptine; neuroendocrine disorders; obesity.

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