Resumen

TABARES NEYRA, Horacio  y  DIAZ QUESADA, Juan Miguel. Relationship between disc degeneration, lumbar pain and stability: Disc degeneration. Rev Cubana Ortop Traumatol [online]. 2015, vol.29, n.2. ISSN 0864-215X.

Aging and degeneration result in changes in the spine; the discs lose their ability to fulfill their functions. A critical review on the intervertebral disc degeneration, pain and stability of the lumbar spine was carried out for which progress in the understanding of disc degeneration process, the influence factors and its cellular processes, as well as the most widely used pathologic classification and its reflection in resonance images were reviewed. The disk cell changes occur through six processes; which causes biochemical changes in the extracellular matrix and loss of function. Cells play the major role in biological and biochemical changes of intervertebral disc degeneration. Genetic predisposition, nutritional and oxygen supply and mechanical stress are involved as other factors in this process, in addition to aging.

Palabras clave : disc degeneration; cells; genetic predisposition; mechanical stress.

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