Introduction:

Dupuytren's disease is a contracture of the palmar fascia due to a fibrous proliferation that causes flexion deformities and loss of function of fingers. It can also be located on the soles of the feet, on the penis or other locations. The cause is unknown.

Objectives:

To describe the disease in two patients with peculiar characteristics at multiple sites.

Conclusions:

The disease is more frequent in males and older than 40 years. The treatment used was fasciectomy surgery plus zetaplasty and amputation.

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