Resumen

BELTRAN SAINZ, Raisa Ivis  y  HERNANDEZ BAGUER, Raisa. Apoptosis and necroptosis in ocular deseases. Rev Cubana Oftalmol [online]. 2016, vol.29, n.1. ISSN 0864-2176.

Apoptosis is a relatively recent term to define a process of programmed cellular death related to different pathological processes (cancer, inflammatory and degenerative diseases). There is currently another process of non-programmed cellular death named necrosis, which occurs through non-modulated mechanisms and a variety is called necroptosis. Both processes (apoptosis and necroptosis) can be found in the physiopathology of some ophthalmological disorders, which prompted us to carry out an updated literature review on this topic. The objective was to increase the amount of knowledge on the topic and its relation to some of the ophthalmological disorders in which it is involved. Basic texts of ophthalmology were reviewed and articles published in the last five years were tracked down using Google as search engine, the LILACS directory and the consultation of the PubMed and Hinari databases. There is still much to be studied on these processes that take place at the cell level and that have only been verified through lab studies and with animal models. Better understanding of this process may pave the way for the emergence of new anti-apoptosis and anti-necroptosis therapies.

Palabras clave : apoptosis; necroptosis; apoptosis and ocular diseases.

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