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Revista Cubana de Oftalmología

versión impresa ISSN 0864-2176versión On-line ISSN 1561-3070

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GARDUNO-VIEYRA, Leopoldo; CASTRO-CAMACHO, Everardo; DE LA FUENTE-BATTA, Isabel  y  LIRA-ALVAREZ, Alejandra. Therapeutic use of hyaluronidase and triamcinolone in orbital pseudotumor. Rev Cubana Oftalmol [online]. 2020, vol.33, n.3, e878.  Epub 02-Nov-2020. ISSN 0864-2176.

The exact etiology of orbital pseudotumor is unknown, but its granulomatous unspecific inflammatory nature at various locations has been recognized. Orbital pseudotumor is defined as a cellular pleomorphic inflammatory response of limited evolution often confined to orbital structures. A case is presented of a female 16-year-old patient diagnosed with orbital pseudotumor confirmed by biopsy and computerized axial tomography, refractory to treatment with systemic steroids, due to which it is decided to start treatment with hyaluronidase and triamcinolone in the peribulbar space. Acute cases often respond fast to treatment with corticosteroids such as prednisone. It should be borne in mind that there are patients who are refractory to treatment for whom alternative treatments should be sought. An option is the use of hyaluronidase to destroy extracellular junctions and locally spread a steroid such as triamcinolone, most effectively within the inflammatory tissue to ensure its localized effect. Total regression of the patient's status was observed at three months of treatment.

Palabras clave : Orbital pseudotumor; hyaluronidase; triamcinolone; exophthalmometry; papilledema.

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